###### Created: 2023-10-17 17:37 ###### Areas & Topics: #medicine #physiology ###### Note Type: #permanent ###### Connected to: [[Non-Steroidal Anti-Inflammatory Drugs (NSAID's)]] [[Thromboxane]] - Prostaglandins are eicosanoids (signalling molecules made from the oxidation of polyunsaturated fatty-acids) which are produced from arachidonic acid by COX enzymes. - They are highly lipophilic, allowing them to enter cells via PGT (Prostaglandin Transporters) and act on receptors to exert their effects. - They have effects in almost every part of the body and appear to be able to cause opposite effects depending on the context they act in. ### Resources https://www.ncbi.nlm.nih.gov/books/NBK553155/